Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876835 | 0.93 | PTPN1 (0.44) | PTPN1CALM1KDM4EMAPTGAA | |
| SCHEMBL18880273 | 0.84 | PTPN1 (0.48) | PTPN1NOS2GABRA1GABRG2GABRB3 | |
| SCHEMBL5528935 | 0.78 | PDE4A (0.36) | PTPN1NOS2CALM1MAPTHSD17B10 | |
| SCHEMBL5534766 | 0.77 | ALDH1A1 (0.38) | PTPN1L3MBTL1CALM1KDM4EMAPT | |
| SCHEMBL18863400 | 0.77 | PTPN1 (0.50) | PTPN1L3MBTL1ABCB1MEN1ALDH1A1 | |
| SCHEMBL18880277 | 0.65 | PTPN1 (0.38) | PTPN1TDP1L3MBTL1GABRA1GABRG2 | |
| SCHEMBL20147805 | 0.64 | FNTA (0.34) | PTPN1NOS2CALM1MAPT | |
| SCHEMBL7511997 | 0.63 | HSD17B10 (0.58) | TDP1L3MBTL1KDM4EMAPTGAA | |
| SCHEMBL6035513 | 0.63 | MAOB (0.65) | APPABCB1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7273091 | 0.63 | MAOB (0.55) | ELANECTSGL3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170149080-A1 | PHOSPHONIUM CATIONS AND POLYMERS INCORPORATING THEM | UNIVERSITY OF DELAWARE (US) | 2017-05-25 | — | — | US | disclosed |