Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424147 | 0.85 | GAA (0.46) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL30577407 | 0.85 | CNR2 (0.48) | GAAKMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL283410 | 0.83 | GAA (0.49) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL10449059 | 0.83 | GAA (0.56) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL858491 | 0.83 | GAA (0.56) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL30331 | 0.82 | GAA (0.55) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL20461221 | 0.82 | GAA (0.55) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL20390738 | 0.82 | GAA (0.55) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL7243879 | 0.82 | GAA (0.55) | GAAKMT2AMEN1ALOX5APP | |
| SCHEMBL753935 | 0.82 | GAA (0.55) | GAAKMT2AMEN1ALOX5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145188-A1 | THERMOPLASTIC COMPOSITIONS SUITABLE FOR USE IN FILMS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-05-25 | — | — | US | disclosed |