SCHEMBL3424147

SCHEMBL3424147

CC(CCCOC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)OC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.46
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.42
ALOX5 P09917 1/20 0.39
HMGCR P04035 2/20 0.38
APP P05067 1/20 0.36
HTT P42858 2/20 0.36
PKM P14618 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
AGTR1 P30556 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10998107 0.95 GAA (0.44) GAAKMT2AMEN1ALOX5HMGCR
SCHEMBL283410 0.89 GAA (0.49) GAAKMT2AMEN1ALOX5HMGCR
SCHEMBL9245230 0.88 GAA (0.48) GAAKMT2AMEN1ALOX5HMGCR
SCHEMBL27931228 0.87 GAA (0.50) GAAKMT2AMEN1HMGCRALDH1A1
SCHEMBL858491 0.86 GAA (0.56) GAAKMT2AMEN1ALOX5APP
SCHEMBL10449059 0.86 GAA (0.56) GAAKMT2AMEN1ALOX5APP
SCHEMBL21616895 0.86 GAA (0.49) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL424069 0.86 GAA (0.49) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL284070 0.85 GAA (0.48) GAAKMT2AMEN1ALOX5HMGCR
SCHEMBL18877342 0.85 GAA (0.43) GAAKMT2AMEN1ALOX5HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863359-B2 Method of preparing transparent copolymer resin, transparent copolymer resin prepared by the method, and resin blend composition including the transparent copolymer resin LG CHEM, LTD. (KR) 2011-01-04 US claimed
US-20060128848-A1 Method of preparing transparent copolymer resin, transparent copolymer resin prepared by the method, and resin blend composition including the transparent copolymer resin LG CHEM, LTD. (KR) 2006-06-15 US claimed
US-8198367-B2 Thermoplastic acrylonitrile-butadiene-styrene resin composition with excellent releasability and colorability LG CHEM, LTD. (KR) 2012-06-12 US disclosed
EP-2157129-B1 Thermoplastic acrylonitrile-butadiene-styrene resin composition with excellent releasability and colorability LG CHEMICAL LTD (KR) 2012-05-16 EP disclosed
US-7863359-B2 Method of preparing transparent copolymer resin, transparent copolymer resin prepared by the method, and resin blend composition including the transparent copolymer resin LG CHEM, LTD. (KR) 2011-01-04 US disclosed
US-20100048798-A1 Thermoplastic Acrylonitrile-Butadiene-Styrene Resin Composition With Excellent Releasability And Colorability LG CHEM, LTD. (KR) 2010-02-25 US disclosed
EP-2157129-A1 Thermoplastic acrylonitrile-butadiene-styrene resin composition with excellent releasability and colorability LG Chem, Ltd. (KR) 2010-02-24 EP disclosed
US-20060128848-A1 Method of preparing transparent copolymer resin, transparent copolymer resin prepared by the method, and resin blend composition including the transparent copolymer resin LG CHEM, LTD. (KR) 2006-06-15 US disclosed
US-5939232-A MULTILAYER; STRIPPABLE SUBSTRATE, TRANSPARENT POLYMERIC ISOLATION LAYER, ELASTOMER, PIGMENTED PHOTOSENSITIVE PHOTOPOLYMERIZABLE LAYER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-17 US disclosed
US-5882753-A Extrudable release coating MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-16 US disclosed
US-5834541-A A BLENDS COMPRISING AN ACID NEUTRALIZING AGENT OTHER THAN METALLIC SALT OF FATTY ACID AND STABILIZERS INCLUDING A PHOSPHITE, A N,N-DIALKYLHYDROXYLAMINE, A BENZOFURANONE; HEAT AND OXIDATION RESISTANCE, NONVOLATILITY MONTELL NORTH AMERICA INC. (US) 1998-11-10 US disclosed
US-4394435-A POLYISOPRENE, PHOTOPOLYMERIZATION UNIROYAL, INC. (US) 1983-07-19 US disclosed
EP-0076588-A2 Syndiotactic polybutadiene composition for photosensitive printing plate UNIROYAL, INC. (US) 1983-04-13 EP disclosed
US-4304712-A CONSTRUCTION MATERIALS THE B. F. GOODRICH COMPANY (US) 1981-12-08 US disclosed
EP-0040934-A1 Expandable thermoplastic composition and method for preparing an expandable article therefrom UNIROYAL, INC. (US) 1981-12-02 EP disclosed
US-4242245-A BARIUM SULFATE; SUBSTITUTED PHENOL, GLYCOL, OR POLYOL PHILLIPS PETROLEUM COMPANY (US) 1980-12-30 US disclosed
US-4133799-A Benzofuranylphenol stabilizers THE B. F. GOODRICH COMPANY (US) 1979-01-09 US disclosed
US-4054551-A Benzofuranylphenol stabilizers THE B. F. GOODRICH COMPANY (US) 1977-10-18 US disclosed
US-4035444-A GREEN STRENGTH THE B. F. GOODRICH COMPANY (US) 1977-07-12 US disclosed
US-3940364-A Naphthofuranylnaphthol stabilizers THE B. F. GOODRICH COMPANY (US) 1976-02-24 US disclosed