SCHEMBL18877734

SCHEMBL18877734

CC(C)(C)C1=CC(=CN=Nc2ccc(F)cc2F)C=C(C(C)(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.36
▸ ATM Q13315 2/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ GPR35 Q9HC97 1/20 0.36
▸ MAPT P10636 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877783 0.93 MAPT (0.32) NPC1ATMKMT2AGPR35MAPT
SCHEMBL18877741 0.84 SMN1; SMN2 (0.43) NPC1ATMKMT2AGPR35MAPT
SCHEMBL13580316 0.83 ATM (0.34) NPC1ATMKMT2AGPR35MAPT
SCHEMBL18877746 0.82 ATM (0.35) NPC1ATMKMT2AGPR35MAPT
SCHEMBL15893570 0.81 NPC1 (0.36) NPC1ATMKMT2AGPR35MAPT
SCHEMBL18877737 0.79 KMT2A (0.38) NPC1ATMKMT2AGPR35MAPT
SCHEMBL18877732 0.78 ATM (0.36) NPC1ATMKMT2AGPR35MAPT
SCHEMBL13580329 0.77 KMT2A (0.39) NPC1ATMKMT2AGPR35MAPT
SCHEMBL13580312 0.76 NPC1 (0.36) NPC1ATMKMT2AGPR35SMN1; SMN2
SCHEMBL13580322 0.76 NPC1 (0.36) NPC1ATMKMT2AGPR35SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197161-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC EQUIPMENT FUJI ELECTRIC CO., LTD. (JP) 2022-06-23 — — US disclosed
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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