SCHEMBL18877783

SCHEMBL18877783

CC1=CC(=CN=Nc2ccc(F)cc2F)C=C(C(C)(C)C)C1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.32
▸ NPC1 O15118 2/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877734 0.93 NPC1 (0.36) MAPTNPC1KMT2AATMGPR35
SCHEMBL18877804 0.83 PTGS1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL18877780 0.79 NPC1 (0.33) NPC1KMT2AATMGPR35
SCHEMBL18877741 0.77 SMN1; SMN2 (0.43) MAPTNPC1KMT2AATMGPR35
SCHEMBL13580316 0.76 ATM (0.34) MAPTNPC1KMT2AATMGPR35
SCHEMBL18877746 0.76 ATM (0.35) MAPTNPC1KMT2AATMGPR35
SCHEMBL18877773 0.76 GSK3B (0.36) MAPTKMT2A
SCHEMBL13580441 0.75 — —
SCHEMBL18877771 0.75 NPC1 (0.32) MAPTNPC1KMT2AATMGPR35
SCHEMBL18877802 0.75 SMN1; SMN2 (0.34) MAPTNPC1KMT2AATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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