SCHEMBL18877735

SCHEMBL18877735

CC(C)(C)C1=CC(=CN=Nc2ccc(Br)cc2Br)C=C(C(C)(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ GPR35 Q9HC97 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.30
▸ TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13580428 0.90 NPC1 (0.36) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580312 0.90 NPC1 (0.36) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580349 0.85 NPC1 (0.33) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580366 0.84 NPC1 (0.33) NPC1KMT2AATMGPR35HSP90AA1
SCHEMBL18877740 0.84 SMN1; SMN2 (0.43) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580387 0.83 NPC1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL13580371 0.83 NPC1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL13580842 0.83 NPC1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL13580306 0.83 NPC1 (0.34) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL18877738 0.82 ATM (0.35) NPC1KMT2AATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
Send feedback