SCHEMBL18877740

SCHEMBL18877740

CC(C)(C)C1=CC(=CN=Nc2ccccc2Br)C=C(C(C)(C)C)C1=O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ NPC1 O15118 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ ATM Q13315 1/20 0.35
▸ GPR35 Q9HC97 1/20 0.35
▸ MEN1 O00255 1/20 0.33
▸ ALPL P05186 1/20 0.33
▸ ALPI P09923 1/20 0.33
▸ ALPG P10696 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ POLB P06746 1/20 0.31
▸ GPR55 Q9Y2T6 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA4 P22748 1/20 0.31
▸ CA6 P23280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13580416 0.86 SMN1; SMN2 (0.44) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL18877735 0.84 NPC1 (0.36) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580312 0.84 NPC1 (0.36) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL18877741 0.83 SMN1; SMN2 (0.43) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL18877733 0.83 SMN1; SMN2 (0.43) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL14280240 0.81 SMN1; SMN2 (0.41) SMN1; SMN2NPC1KMT2AMEN1RAB9A
SCHEMBL13580399 0.80 SMN1; SMN2 (0.32) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL21179846 0.80 SMN1; SMN2 (0.40) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13986184 0.80 SMN1; SMN2 (0.40) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580306 0.80 NPC1 (0.34) SMN1; SMN2NPC1KMT2AATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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