SCHEMBL18877751

SCHEMBL18877751

CC(C)(C)C1=CC(=C(N=Nc2ccc(Cl)cc2Cl)c2ccccc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ ITGA1 P56199 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ RAB9A P51151 4/20 0.33
▸ NPC1 O15118 3/20 0.33
▸ POLB P06746 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ GFER P55789 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ GPR55 Q9Y2T6 1/20 0.32
▸ S100B P04271 1/20 0.31
▸ CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877752 0.90 MAPT (0.35) SMN1; SMN2MAPTLMNAALDH1A1TDP1
SCHEMBL13580453 0.87 SMN1; SMN2 (0.34) FABP4SMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL18877758 0.86 SMN1; SMN2 (0.33) SMN1; SMN2ITGA1MAPTLMNAALDH1A1
SCHEMBL14594049 0.84 MEN1 (0.33) SMN1; SMN2MAPTLMNATDP1RAB9A
SCHEMBL14593999 0.84 NPC1 (0.33) LMNAALDH1A1RAB9ANPC1POLB
SCHEMBL14593962 0.84 MEN1 (0.33) LMNARAB9ANPC1POLBMEN1
SCHEMBL18877777 0.83 MAPT (0.39) SMN1; SMN2MAPTLMNAALDH1A1L3MBTL1
SCHEMBL18877753 0.82 MEN1 (0.36) SMN1; SMN2MAPTLMNATDP1RAB9A
SCHEMBL13580457 0.81 POLB (0.30) POLB
SCHEMBL18877781 0.81 SMN1; SMN2 (0.34) SMN1; SMN2POLBGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197161-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC EQUIPMENT FUJI ELECTRIC CO., LTD. (JP) 2022-06-23 — — US disclosed
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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