SCHEMBL18877752

SCHEMBL18877752

Cc1ccc(C(N=Nc2ccc(Cl)cc2Cl)=C2C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.35
▸ NPC1 O15118 3/20 0.35
▸ RAB9A P51151 3/20 0.35
▸ HPGD P15428 2/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ POLB P06746 1/20 0.34
▸ GFER P55789 1/20 0.34
▸ MGAM O43451 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SI P14410 1/20 0.33
▸ MGAM2 Q2M2H8 1/20 0.33
▸ CES2 O00748 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ LMNA P02545 5/20 0.32
▸ HTT P42858 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ CRHBP P24387 1/20 0.32
▸ CRHR2 Q13324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877751 0.90 FABP4 (0.35) MAPTNPC1RAB9AHPGDSMN1; SMN2
SCHEMBL18877760 0.86 MGAM (0.34) MAPTNPC1RAB9AHPGDSMN1; SMN2
SCHEMBL18877795 0.83 MAPT (0.47) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL14593962 0.83 MEN1 (0.33) NPC1RAB9AKMT2AMEN1POLB
SCHEMBL14593999 0.83 NPC1 (0.33) NPC1RAB9AHPGDKMT2AMEN1
SCHEMBL13580457 0.83 POLB (0.30) POLB
SCHEMBL18877796 0.81 NPC1 (0.32) NPC1KMT2AMEN1GAA
SCHEMBL18877775 0.81 MEN1 (0.32) MAPTNPC1RAB9AKMT2AMEN1
SCHEMBL14594049 0.81 MEN1 (0.33) MAPTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL18877753 0.81 MEN1 (0.36) MAPTNPC1RAB9ASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197161-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC EQUIPMENT FUJI ELECTRIC CO., LTD. (JP) 2022-06-23 — — US disclosed
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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