Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.86 |
| ▸ | DRD3 | P35462 | 8/20 | 0.86 |
| ▸ | DRD4 | P21917 | 4/20 | 0.86 |
| ▸ | HTR1A | P08908 | 2/20 | 0.86 |
| ▸ | DRD1 | P21728 | 2/20 | 0.86 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.86 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.86 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.86 |
| ▸ | CNR1 | P21554 | 1/20 | 0.86 |
| ▸ | ACHE | P22303 | 1/20 | 0.86 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.86 |
| ▸ | HTR2A | P28223 | 1/20 | 0.86 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.86 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.86 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.86 |
| ▸ | HRH1 | P35367 | 1/20 | 0.86 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.86 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9886171 | 1.00 | DRD2 (0.86) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL9405994 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL29354493 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL50425 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL30200958 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL1088585 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL2597402 | 0.92 | DRD2 (0.98) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL2597403 | 0.92 | DRD2 (0.98) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL15970012 | 0.92 | DRD2 (0.98) | DRD2DRD3DRD4HTR1ADRD1 | |
| Rotigotine SCHEMBL30730591 | 0.92 | DRD2 (0.98) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118818-A1 | ENCAPSULATED OR COATED STENT SYSTEMS | Gel-Del Technologies ,Inc. a corporation | 2011-05-19 | — | — | US | disclosed |