SCHEMBL18878282

SCHEMBL18878282

CC1(C)c2cc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccc(-c6ccccc6)cc5)n4)cc3)ccc2-c2c1ccc1ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.37
KMT2A Q03164 6/20 0.37
MAPT P10636 5/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
NTSR1 P30989 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ATM Q13315 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18878316 1.00 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17151655 1.00 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17932706 0.97 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL18878299 0.96 RARA (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22038460 0.96 RARA (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24255974 0.96 MEN1 (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17887180 0.96 RARA (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22038088 0.96 RARA (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL18878308 0.96 MEN1 (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL18878306 0.96 RARA (0.36) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170148995-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-05-25 US disclosed
US-20170148995-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-05-25 US disclosed