SCHEMBL18878348

SCHEMBL18878348

CC(O)COC(=O)OCCOC(C)COCCOC(=O)OCCO

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
HSD17B10 Q99714 1/20 0.34
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15315311 0.94 TDP1 (0.49) TDP1HSD17B10MAPT
SCHEMBL15315312 0.92 TDP1 (0.38) TDP1TSHR
SCHEMBL16589239 0.87 TDP1 (0.42) TDP1HSD17B10MAPT
SCHEMBL17704714 0.87 TDP1 (0.42) TDP1HSD17B10MAPT
SCHEMBL15315315 0.86 ALDH1A1 (0.42) TDP1HSD17B10TSHR
SCHEMBL17704713 0.86 TDP1 (0.34) TDP1
SCHEMBL15440925 0.86 TDP1 (0.34) TDP1TSHR
SCHEMBL9964655 0.78 MAPT (0.44) TDP1HSD17B10MAPTTSHR
SCHEMBL15383094 0.77 TDP1 (0.35) TDP1HSD17B10MAPT
SCHEMBL1471703 0.76 ALDH1A1 (0.47) TDP1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145147-A1 HIGH STRENGTH POLYURETHANE FOAM COMPOSITIONS AND METHODS NOVOMER, INC. 2017-05-25 US disclosed