Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910303 | 0.91 | HTT (0.56) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL463659 | 0.89 | GAA (0.70) | HTTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL822947 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL2606163 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL4569586 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12268296 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL10084171 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822843 | 0.87 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL407203 | 0.85 | TEAD4 (0.54) | HTTSMN1; SMN2TDP1ALDH1A1MEN1 | |
| SCHEMBL15908262 | 0.84 | GAA (0.61) | HTTSMN1; SMN2GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145242-A1 | FLUOROPOLYMER COMPOSITION | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2017-05-25 | — | — | US | disclosed |