SCHEMBL4569586

SCHEMBL4569586

Cc1ccc(Oc2ccc(S(=O)(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.85
SMN1; SMN2 Q16637 3/20 0.85
TDP1 Q9NUW8 2/20 0.73
L3MBTL1 Q9Y468 1/20 0.73
GAA P10253 2/20 0.73
PKM P14618 4/20 0.58
FFAR1 O14842 1/20 0.54
ALDH1A1 P00352 5/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TEAD4 Q15561 1/20 0.52
LMNA P02545 2/20 0.52
POLB P06746 2/20 0.50
RAPGEF4 Q8WZA2 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
GFER P55789 1/20 0.49
CA1 P00915 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822843 1.00 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL2606163 1.00 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL822947 1.00 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL12268296 1.00 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL10084171 1.00 HTT (0.85) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL23957972 0.94 HTT (0.76) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL12769542 0.94 HTT (0.76) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL822844 0.94 HTT (0.76) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL16621782 0.94 HTT (0.76) HTTSMN1; SMN2TDP1L3MBTL1GAA
SCHEMBL17247214 0.94 HTT (0.76) HTTSMN1; SMN2TDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142592-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR TOSOH CORPORATION (JP) 2023-05-11 US disclosed
US-10961350-B2 Polymer composition and sterilizable articles obtainable therefrom SOLVAY SPECIALTY POLYMERS USA, INC. (US) 2021-03-30 US disclosed
EP-3174937-B1 POLYMERIC MATERIALS VICTREX MFG LTD (GB) 2019-03-27 EP disclosed
US-9178238-B2 Rubber crack mitigants in polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, LLC (US) 2015-11-03 US disclosed
US-9178238-B2 Rubber crack mitigants in polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, LLC (US) 2015-11-03 US disclosed
US-9172099-B2 Nano-fibers for electrical power generation GM Global Technology Operations LLC (US) 2015-10-27 US disclosed
US-9172099-B2 Nano-fibers for electrical power generation GM Global Technology Operations LLC (US) 2015-10-27 US disclosed
US-20150171454-A1 MEMBRANE WITH LAMINATED STRUCTURE AND ORIENTATION CONTROLLED NANOFIBER REINFORCEMENT ADDITIVES FOR FUEL CELLS GM GLOBAL TECH OPERATIONS INC (US) 2015-06-18 US disclosed
US-20150171454-A1 MEMBRANE WITH LAMINATED STRUCTURE AND ORIENTATION CONTROLLED NANOFIBER REINFORCEMENT ADDITIVES FOR FUEL CELLS GM GLOBAL TECH OPERATIONS INC (US) 2015-06-18 US disclosed
US-9040209-B2 Multi-layer polyelectrolyte membranes GM Global Technology Operations LLC (US) 2015-05-26 US disclosed
US-7888433-B2 Sulfonated-polyperfluoro-cyclobutane-polyphenylene polymers for PEM fuel cell applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-02-15 US disclosed
US-7888433-B2 Sulfonated-polyperfluoro-cyclobutane-polyphenylene polymers for PEM fuel cell applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-02-15 US disclosed
US-20100047657-A1 GRADIENT REINFORCED PROTON EXCHANGE MEMBRANE GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2010-02-25 US disclosed
US-20100047657-A1 GRADIENT REINFORCED PROTON EXCHANGE MEMBRANE GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2010-02-25 US disclosed
US-20090281270-A1 SULFONATED-POLYPERFLUORO-CYCLOBUTANE-POLYPHENLENE POLYMERS FOR PEM FUEL CELL APPLICATIONS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090280383-A1 BLENDED PEM'S WITH ELASTOMERS FOR IMPROVED MECHANICAL DURABILITY GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090280382-A1 COMPOSITE MEMBRANE GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090278083-A1 POLYELECTROLYTE MEMBRANES COMPRISED OF BLENDS OF PFSA AND SULFONATED PFCB POLYMERS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142592-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR CHRM1, CHRM2, ACVRL1 HTT 3540/4885SMN1; SMN2 3596/4885TDP1 2423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.