Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | ITGAL | P20701 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028689 | 0.90 | ITGB2 (0.57) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL1133307 | 0.90 | ITGB2 (0.57) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL1132649 | 0.90 | ITGB2 (0.57) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL18814494 | 0.89 | REN (0.49) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL28684251 | 0.89 | ITGB2 (0.56) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL1486141 | 0.89 | REN (0.49) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL13187470 | 0.87 | ITGB2 (0.49) | RENHRH3ITGB2ICAM1ITGAL | |
| SCHEMBL26144463 | 0.85 | REN (0.57) | REN | |
| SCHEMBL13609238 | 0.84 | HRH3 (0.51) | HRH3 | |
| SCHEMBL29290115 | 0.83 | REN (0.55) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170812-A1 | IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME | Fujifilm Corporation (JP) | 2017-05-24 | — | — | EP | disclosed |