Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21081224 | 0.84 | SIGMAR1 (0.47) | GAAOPRM1OPRD1MRGPRX2KDM4E | |
| SCHEMBL21173102 | 0.84 | SIGMAR1 (0.47) | GAAOPRM1OPRD1MRGPRX2KDM4E | |
| SCHEMBL18994724 | 0.82 | GAA (0.67) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL12960964 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL14371364 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL12717590 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL21148321 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL12717587 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL13301309 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 | |
| SCHEMBL18457700 | 0.81 | GAA (1.00) | GAAOPRM1OPRD1OPRK1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656961-B2 | Methods for treating depressive symptoms | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-05-23 | — | — | US | disclosed |