Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | PKLR | P30613 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072184 | 0.87 | MAPT (0.44) | HTTPKMPKLRRIPK1LTA4H | |
| SCHEMBL14803381 | 0.87 | MAPT (0.44) | HTTPKMPKLRRIPK1LTA4H | |
| SCHEMBL18879751 | 0.82 | SMN1; SMN2 (0.43) | HTTLTA4HMAPTLMNAKDM4E | |
| SCHEMBL18879757 | 0.82 | SMN1; SMN2 (0.43) | HTTLTA4HMAPTLMNAKDM4E | |
| SCHEMBL2924947 | 0.76 | CTNNB1 (0.53) | HTTPKMPKLRMAPTLMNA | |
| SCHEMBL18071258 | 0.74 | PRKDC (0.41) | PKMPKLRLTA4HMAPTHPGD | |
| SCHEMBL30507863 | 0.73 | CTNNB1 (0.46) | PKMPKLRMAPTKDM4EALDH1A1 | |
| SCHEMBL20867781 | 0.73 | KDM4E (0.59) | HTTPKMPKLRMAPTLMNA | |
| SCHEMBL20348516 | 0.73 | ALDH1A1 (0.50) | HTTPKMPKLRRIPK1AKR1B1 | |
| SCHEMBL27352624 | 0.72 | SMN1; SMN2 (0.52) | HTTLMNAKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655982-B2 | Formation and uses of europium complexes | WAYNE STATE UNIVERSITY (US) | 2017-05-23 | — | — | US | disclosed |