Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.36 |
| ▸ | KDM5C | P41229 | 6/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 5/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18860200 | 0.85 | SIRT2 (0.41) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16303307 | 0.80 | SIRT2 (0.38) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16305525 | 0.76 | TERT (0.44) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16292979 | 0.72 | CHRM2 (0.41) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16305488 | 0.71 | CHRM2 (0.43) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL18017098 | 0.71 | SIRT2 (0.42) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16006936 | 0.70 | CXCR4 (0.39) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16293473 | 0.70 | TERT (0.39) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL16305531 | 0.70 | TERT (0.39) | SIRT2TERTCCNA2CDK2KDM5B | |
| SCHEMBL17984971 | 0.70 | CHRM2 (0.40) | SIRT2TERTCCNA2CDK2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170811-A1 | ETHYL PYRIDINE-4-CARBOXYLATE COMPOUND AS INHIBITOR OF HISTONE DEMETHYLASES | Gilead Sciences, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |