Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 12/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880976 | 0.89 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL18880982 | 0.76 | SLC28A1 (0.35) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL18880981 | 0.74 | P2RY6 (0.33) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL784257 | 0.73 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL26289942 | 0.72 | P2RY6 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL51723 | 0.69 | SLC28A1 (0.45) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL18880978 | 0.69 | POLB (0.35) | DUT | |
| Hydrochloric Acid SCHEMBL27782735 | 0.68 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL17807711 | 0.68 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL19245183 | 0.68 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794629-B1 | 2',4'-DIFLUORO-2'-METHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | RIBOSCIENCE LLC (US) | 2017-05-24 | — | — | EP | disclosed |