SCHEMBL51723

SCHEMBL51723

O=c1ccn([C@@]2(F)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.45
SLC28A2 O43868 1/20 0.45
SLC29A1 Q99808 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.45
P2RY6 Q15077 8/20 0.40
P2RY2 P41231 1/20 0.35
P2RY4 P51582 1/20 0.35
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
P2RY14 Q15391 1/20 0.34
DUT P33316 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27782735 0.99 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Phosphoric Acid SCHEMBL27944541 0.95 P2RY6 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Phosphoric Acid SCHEMBL7594885 0.95 P2RY6 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL30388810 0.93 P2RY6 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4952061 0.90 SLC28A1 (0.38) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29783611 0.90 P2RY6 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Triphosphate SCHEMBL27901431 0.89 P2RY6 (0.53) P2RY6P2RY2P2RY4
SCHEMBL6851760 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Fluorouracil SCHEMBL16835735 0.88 LMNA (0.38) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28786348 0.85 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10678 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570704-B2 Functionally modified maytansinoids and compositions and methods of use thereof University of Georgie Research Foundation, Inc. (US) 2026-03-10 US claimed
US-20250268993-A1 ALKALINE PHOSPHATE-BASED ONCOLOGY TREATMENTS THERIVA BIOLOGICS, INC. 2025-08-28 US claimed
CN-120138086-A Process for preparing nucleoside analogues 正大天晴药业集团股份有限公司 2025-06-13 CN claimed
US-12318434-B2 Alkaline phosphate-based oncology treatments THERIVA BIOLOGICS, INC. (US) 2025-06-03 US claimed
EP-4558641-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS Guardant Health, Inc. (US) 2025-05-28 EP claimed
CN-119923475-A Method for detecting and reducing sample preparation induced methylation artifacts 夸登特健康公司 2025-05-02 CN claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
US-20250116671-A1 Kinase Activity In Tumors INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-04-10 US claimed
CN-119638766-A Method for separating and purifying fluoronucleoside 中国科学院青岛生物能源与过程研究所 2025-03-18 CN claimed
CN-119630427-A Anti-FGFR 3 antibody conjugates and medical uses thereof 启德医药科技(苏州)有限公司 2025-03-14 CN claimed
WO-1991017660-A1 5,10-METHYLENE-TETRAHYDROFOLATE AS A MODULATOR OF A CHEMOTHERAPEUTIC AGENT SPEARS COLIN P (US) 1991-11-28 WO claimed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO claimed
EP-0352988-A2 Polynucleotide probes for horses HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND (NZ) 1990-01-31 EP claimed
CN-88102026-A CHEMO-RADIO-IMMUNO-CONJUGATES 1988-09-28 CN claimed
EP-0282057-A2 Chemo-radio-immuno-conjugates THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1988-09-14 EP claimed
US-4585736-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-4416875-A ANTITUMOR AGENTS FUNAI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1983-11-22 US claimed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP claimed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP claimed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO claimed