Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15423515 | 0.86 | ADORA3 (0.39) | ADORA3ADORA2AADORA2BADORA1PDE4B | |
| SCHEMBL15424496 | 0.80 | NTRK1 (0.35) | ADORA2AADORA2BADORA1NTRK1LTK | |
| SCHEMBL31205288 | 0.73 | ADORA2A (0.41) | ADORA2AADORA2BADORA1NTRK1LTK | |
| SCHEMBL17865293 | 0.72 | NTRK1 (0.37) | ADORA2AADORA1NTRK1LTKTYRO3 | |
| SCHEMBL11327423 | 0.70 | MAPT (0.47) | — | |
| SCHEMBL21610583 | 0.68 | ADORA3 (0.32) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL21129246 | 0.67 | HTR2A (0.35) | — | |
| SCHEMBL10414406 | 0.67 | — | — | |
| SCHEMBL21477591 | 0.67 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1ELANE | |
| SCHEMBL17297731 | 0.67 | ADORA2A (0.58) | ADORA3ADORA2AADORA2BADORA1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |