Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19447856 | 0.93 | BCHE (0.39) | BCHEACHEALDH1A1MAPK14PRMT5 | |
| SCHEMBL15423517 | 0.87 | ALDH1A1 (0.40) | BCHEACHEALDH1A1MAPK14LMNA | |
| SCHEMBL1616244 | 0.81 | BCHE (0.45) | BCHEACHEALDH1A1MAPK14PRMT5 | |
| SCHEMBL13487023 | 0.77 | MAPK14 (0.46) | BCHEACHEALDH1A1MAPK14LMNA | |
| SCHEMBL21657799 | 0.77 | — | — | |
| SCHEMBL11327423 | 0.77 | MAPT (0.47) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL22793039 | 0.75 | NPSR1 (0.34) | BCHEACHEALDH1A1MAPK14LMNA | |
| SCHEMBL22335311 | 0.74 | BCHE (0.41) | BCHEACHEALDH1A1MAPK14PRMT5 | |
| SCHEMBL23178620 | 0.73 | BCHE (0.40) | BCHEACHEALDH1A1MAPK14PRMT5 | |
| SCHEMBL23178935 | 0.73 | ALDH1A1 (0.38) | BCHEACHEALDH1A1MAPK14PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |