Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 14/20 | 0.66 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965706 | 0.83 | CMA1 (0.44) | CMA1AKR1B1AR | |
| SCHEMBL18900941 | 0.82 | CMA1 (0.79) | CMA1CTSG | |
| SCHEMBL7960258 | 0.80 | CMA1 (1.00) | CMA1CTSGAKR1B1 | |
| SCHEMBL6115259 | 0.79 | CMA1 (1.00) | CMA1CTSG | |
| SCHEMBL6115315 | 0.77 | CMA1 (0.67) | CMA1CTSGAKR1B1 | |
| SCHEMBL1847165 | 0.76 | CMA1 (0.80) | CMA1 | |
| SCHEMBL1848893 | 0.74 | AR (0.63) | CMA1AR | |
| SCHEMBL7961797 | 0.74 | CMA1 (0.78) | CMA1CTSG | |
| SCHEMBL18900823 | 0.73 | CMA1 (0.79) | CMA1CTSG | |
| SCHEMBL7951286 | 0.72 | CMA1 (1.00) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |