Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 11/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960258 | 0.88 | CMA1 (1.00) | CMA1MAPTCTSGCYP1A2CYP3A4 | |
| SCHEMBL6115259 | 0.87 | CMA1 (1.00) | CMA1MAPTCTSGCYP1A2CYP3A4 | |
| SCHEMBL1847165 | 0.86 | CMA1 (0.80) | CMA1RECQLCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900854 | 0.86 | CMA1 (0.76) | CMA1MAPTRECQLALOX15 | |
| SCHEMBL18887412 | 0.82 | CMA1 (0.66) | CMA1CTSG | |
| SCHEMBL7961797 | 0.82 | CMA1 (0.78) | CMA1MAPTRECQLCTSGCYP1A2 | |
| SCHEMBL18900837 | 0.81 | CMA1 (0.77) | CMA1CTSG | |
| SCHEMBL6115315 | 0.81 | CMA1 (0.67) | CMA1CTSGCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900823 | 0.81 | CMA1 (0.79) | CMA1CTSG | |
| SCHEMBL7951286 | 0.79 | CMA1 (1.00) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |