SCHEMBL18889484

SCHEMBL18889484

CCCCCC/C=C/C=C/C=C/C(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.61
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.59
TSHR P16473 1/20 0.59
CNR1 P21554 2/20 0.57
CNR2 P34972 2/20 0.57
PTPN1 P18031 1/20 0.53
FAAH O00519 2/20 0.51
GMNN O75496 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
ALOX15 P16050 1/20 0.50
APEX1 P27695 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26461191 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL3134777 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL29691723 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL28666981 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL11925454 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL3134783 1.00 FASN (0.61) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL5912076 0.98 FASN (0.63) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL7749287 0.98 FASN (0.63) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL4732258 0.98 FASN (0.63) FASNKDM4EALDH1A1TSHRCNR1
SCHEMBL21858122 0.98 FASN (0.63) FASNKDM4EALDH1A1TSHRCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10183922-B2 Methods and compositions for wound healing QBIOTICS LIMITED (AU) 2019-01-22 US disclosed
US-20170144981-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING QBIOTICS LIMITED (AU) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10183922-B2 Methods and compositions for wound healing PTGES3, ELANE, PTGES FASN 7/4885KDM4E 776/4885ALDH1A1 330/4885
US-20170144981-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING PTGES3, ELANE, PTGES FASN 7/4885KDM4E 776/4885ALDH1A1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.