Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | PARP1 | P09874 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30517110 | 1.00 | POLB (0.62) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL11673649 | 0.89 | CYP1B1 (0.54) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL3301206 | 0.87 | PARP1 (0.49) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL8482582 | 0.85 | KDR (0.48) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL29532065 | 0.85 | KDR (0.48) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL7118963 | 0.85 | CDK5 (0.54) | POLBPARP1CYP1A2NPSR1MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL18319432 | 0.85 | POLB (0.48) | POLBPARP1CYP1A2NPSR1MEN1 | |
| SCHEMBL77179 | 0.84 | CYP1B1 (0.61) | POLBCYP1A2MEN1MAPTKMT2A | |
| SCHEMBL29583035 | 0.84 | CYP1B1 (0.61) | POLBCYP1A2MEN1MAPTKMT2A | |
| SCHEMBL18319694 | 0.82 | POLB (0.44) | POLBPARP1CYP1A2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332847-B | AIE active naphthalimide compound containing methylthio and preparation method and application thereof | 上海工程技术大学 | 2025-02-11 | — | — | CN | claimed |
| CN-118221666-A | Near-infrared aggregation-induced emission molecule, and preparation method and application thereof | 上海工程技术大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118184626-A | Fluorescent dye for cell nucleus marking and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-115521256-B | Preparation method of 4-amino-1, 8-naphthalimide derivative | 齐鲁工业大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117327111-A | Probe for rapidly detecting hydrogen peroxide in high-sensitivity colorimetric and fluorescent modes, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2024-01-02 | — | — | CN | claimed |
| CN-116731582-B | Acrylic resin fluorescent luminous paint and preparation method thereof | 南通市乐佳涂料有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-117024462-A | sulfonamide-naphthalimide-TB derivative and synthetic method and application thereof | 江苏师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116874423-A | Aldehyde molecular probe and preparation method and application thereof | 华纺股份有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116731582-A | Acrylic resin fluorescent luminous paint and preparation method thereof | 南通市乐佳涂料有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116332847-A | AIE active naphthalimide compound containing methylthio and preparation method and application thereof | 上海工程技术大学 | 2023-06-27 | — | — | CN | claimed |
| WO-2007064345-A9 | HETEROCYCLIC-SUBSTITUTED BIS-1,8 NAPHTHALIMIDE COMPOUNDS, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE | GENENTECH INC (US) | 2007-07-12 | — | — | WO | claimed |
| US-20060182751-A1 | Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use | GENENTECH, INC. (US) | 2006-08-17 | — | — | US | claimed |
| EP-1206456-B1 | THERMOCHROMIC RYLENE DYES | BASF AG (DE) | 2004-11-17 | — | — | EP | claimed |
| US-6486319-B1 | Thermochromic rylene dyes | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | claimed |
| EP-0698230-A1 | CHEMICALLY AMPLIFIED PHOTORESIST | International Business Machines Corporation (US) | 1996-02-28 | — | — | EP | claimed |
| JP-H08501890-A | — | — | 1996-02-27 | — | — | JP | claimed |
| EP-0698230-A4 | CHEMICALLY AMPLIFIED PHOTORESIST | IBM (US) | 1995-10-24 | — | — | EP | claimed |
| WO-1994010608-A9 | CHEMICALLY AMPLIFIED PHOTORESIST | — | 1994-07-21 | — | — | WO | claimed |
| WO-1994010608-A1 | CHEMICALLY AMPLIFIED PHOTORESIST | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-05-11 | — | — | WO | claimed |
| US-4181530-A | ELECTRON ATTRACTING PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060182751-A1 | Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use | CCNY, CCNI, MKI67 | POLB 502/4885PARP1 79/4885CYP1A2 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.