SCHEMBL77179

SCHEMBL77179

O=C1C(=O)c2ccc(Br)c3cccc1c23

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 16/20 0.61
CYP1A2 P05177 1/20 0.56
ALDH1A1 P00352 3/20 0.56
POLB P06746 2/20 0.56
RXFP1 Q9HBX9 1/20 0.56
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
PABPC1 P11940 1/20 0.50
KMT2A Q03164 1/20 0.50
CES2 O00748 1/20 0.50
BCHE P06276 1/20 0.50
CES1 P23141 1/20 0.50
MCL1 Q07820 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583035 1.00 CYP1B1 (0.61) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL10350796 0.94 PABPC1 (0.58) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL29698127 0.90 PABPC1 (0.64) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL17322323 0.90 PABPC1 (0.64) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL29907914 0.90 PABPC1 (0.64) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL1983882 0.90 PABPC1 (0.64) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL28598724 0.86 CYP1B1 (0.49) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL320954 0.85 TYMS (0.61) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL29362967 0.85 TYMS (0.61) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL2800725 0.84 BCL2 (0.63) CYP1B1CYP1A2ALDH1A1POLBRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384735-B Application of composite fluorescent probe in imaging detection of tumor living cells 重庆问创基因科技有限公司 2022-07-19 CN claimed
CN-107417632-B Preparation method of inorganic-organic composite titanium dioxide quantum dots and application of inorganic-organic composite titanium dioxide quantum dots in tumor cell imaging detection 河南师范大学 2020-04-21 CN claimed
CN-117447410-A Dicyanoacenaphthopyrazine TSCT-TADF near infrared luminescent material and application thereof 常州大学 2024-01-26 CN disclosed
US-20230372496-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 THERAPEUTICS, INC. (US) 2023-11-23 US disclosed
US-20230372496-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 THERAPEUTICS, INC. (US) 2023-11-23 US disclosed
CN-116723839-A Tricyclic heterobifunctional compounds for degrading target proteins C4医药公司 2023-09-08 CN disclosed
CN-116102441-A Compound, dye and application of compound 上海大学 2023-05-12 CN disclosed
CN-111620841-B 3-cyano phenalenone compound and application thereof 大连理工大学 2023-03-28 CN disclosed
CN-111138373-B Fluorescent probe for detecting nitric oxide concentration and synthetic method and application thereof 大连大学 2022-09-13 CN disclosed
CN-114967329-A Colored resin composition, compound, color filter and display device 住友化学株式会社 2022-08-30 CN disclosed
CN-109384735-B Application of composite fluorescent probe in imaging detection of tumor living cells 重庆问创基因科技有限公司 2022-07-19 CN disclosed
US-7358362-B2 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2008-04-15 US disclosed
US-20080071122-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-03-20 US disclosed
US-20080071122-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-03-20 US disclosed
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2007-07-05 US disclosed
EP-1754696-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-02-21 EP disclosed
EP-1713777-A1 METHOD FOR PRODUCING TERRYLEN-3,4:11,12-TETRACARBON ACID DI-IMIDS BASF AKTIENGESELLSCHAFT (DE) 2006-10-25 EP disclosed
EP-1711469-A1 METHOD FOR THE PRODUCTION OF TERYLENE-3,4:11,12-TETRACARBOXYDIIMIDES BY DIRECT SYNTHESIS BASF AKTIENGESELLSCHAFT (DE) 2006-10-18 EP disclosed
WO-2005070894-A1 METHOD FOR PRODUCING TERRYLEN-3,4:11,12-TETRACARBON ACID DI-IMIDS BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 WO disclosed
WO-2005070895-A1 METHOD FOR THE PRODUCTION OF TERYLENE-3,4:11,12-TETRACARBOXYDIIMIDES BY DIRECT SYNTHESIS BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372496-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS CRBN, CDR2, MDM2 CYP1B1 1951/4885CYP1A2 3440/4885ALDH1A1 4099/4885
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis HACL2, HRH3, HCN2 CYP1B1 748/4885CYP1A2 182/4885ALDH1A1 3629/4885
US-20080071122-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, EFNA1, L1CAM CYP1B1 813/4885CYP1A2 1650/4885ALDH1A1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.