Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890873 | 0.81 | MAPT (0.65) | MAPTSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL23769038 | 0.74 | MAPT (0.74) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL21905570 | 0.72 | MAPT (0.68) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL4515866 | 0.70 | HPGD (0.51) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL21972114 | 0.69 | MAPT (1.00) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL23769051 | 0.69 | MAPT (0.64) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL29978899 | 0.69 | MAPT (0.64) | MAPTSMN1; SMN2TP53KDM4EALDH1A1 | |
| SCHEMBL30016367 | 0.68 | CPT1A (1.00) | MAPTKDM4ENPC1MAPK1PPARG | |
| SCHEMBL751881 | 0.68 | CPT1A (1.00) | MAPTKDM4ENPC1MAPK1PPARG | |
| SCHEMBL25037402 | 0.68 | STING1 (0.50) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170146519-A1 | STING AGONISTS AND METHODS OF SELECTING STING AGONISTS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170146519-A1 | STING AGONISTS AND METHODS OF SELECTING STING AGONISTS | STING1, IRF3, MAVS | MAPT 4720/4885SMN1; SMN2 3692/4885TP53 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.