SCHEMBL18891297

SCHEMBL18891297

CC(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 4/20 0.50
▸ NPY4R P50391 4/20 0.50
▸ NPY1R P25929 3/20 0.50
▸ TFPI P10646 1/20 0.49
▸ QRFPR Q96P65 1/20 0.49
▸ NPY2R P49146 1/20 0.49
▸ OPRD1 P41143 6/20 0.49
▸ OPRM1 P35372 5/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ OPRL1 P41146 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18556709 0.89 OPRD1 (0.51) TFPIQRFPROPRD1OPRM1OPRK1
SCHEMBL30924733 0.85 TFPI (0.56) TFPIQRFPROPRL1
SCHEMBL30924743 0.85 TFPI (0.56) NPY5RNPY4RNPY1RTFPINPY2R
SCHEMBL24713147 0.85 NPY4R (0.58) NPY5RNPY4RNPY1RQRFPRNPY2R
SCHEMBL24713048 0.84 QRFPR (0.53) NPY5RNPY4RNPY1RQRFPRNPY2R
SCHEMBL24488464 0.84 NPY4R (0.49) NPY5RNPY4RNPY1RQRFPRNPY2R
SCHEMBL24158319 0.84 TFPI (0.48) NPY5RNPY4RNPY1RTFPIQRFPR
SCHEMBL30688407 0.83 NPY4R (0.57) NPY5RNPY4RNPY1RTFPINPY2R
SCHEMBL31563618 0.83 NPY4R (0.59) NPY5RNPY4RNPY1RNPY2ROPRD1
SCHEMBL10786338 0.83 OPRD1 (0.64) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2017-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC5R, MC3R NPY5R 6/4885NPY4R 9/4885NPY1R 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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