Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14663766 | 1.00 | REN (0.81) | REN | |
| SCHEMBL8285264 | 1.00 | REN (0.81) | REN | |
| SCHEMBL19236105 | 0.92 | REN (0.75) | REN | |
| SCHEMBL14662530 | 0.92 | REN (0.71) | REN | |
| SCHEMBL7875184 | 0.90 | REN (0.87) | REN | |
| SCHEMBL24294145 | 0.90 | REN (0.69) | REN | |
| Aliskiren SCHEMBL7965529 | 0.90 | REN (1.00) | REN | |
| Aliskiren SCHEMBL13320734 | 0.90 | REN (1.00) | REN | |
| Aliskiren SCHEMBL3476537 | 0.90 | REN (1.00) | REN | |
| Aliskiren SCHEMBL455490 | 0.90 | REN (1.00) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480224-B1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MCP-1 MEDIATED INFLAMMATORY DISEASES | ACRAF (IT) | 2017-05-24 | — | — | EP | disclosed |