Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 12/20 | 0.80 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528458 | 0.89 | RXFP1 (1.00) | RXFP1KCNMA1GAAMAPTMAPK1 | |
| SCHEMBL18893298 | 0.85 | KCNK3 (0.75) | RXFP1KCNMA1GAAMAPTMAPK1 | |
| SCHEMBL15528384 | 0.84 | RXFP1 (0.77) | RXFP1MEN1KMT2A | |
| SCHEMBL15528462 | 0.82 | RXFP1 (1.00) | RXFP1GAAMAPTMAPK1MEN1 | |
| SCHEMBL4433023 | 0.78 | KCNK3 (0.84) | RXFP1KCNMA1MAPTKCNK3KCNK9 | |
| SCHEMBL15528334 | 0.78 | RXFP1 (0.74) | RXFP1GAAMAPTMAPK1KCNK3 | |
| SCHEMBL6778380 | 0.77 | SGMS2 (0.76) | RXFP1MAPK1KCNK3KCNK9ALDH1A1 | |
| SCHEMBL13853038 | 0.77 | F2R (0.53) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4433924 | 0.77 | MAPT (0.74) | RXFP1KCNMA1GAAMAPTMAPK1 | |
| SCHEMBL328592 | 0.77 | GAA (0.74) | RXFP1KCNMA1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | RXFP1 1/4885KCNMA1 1505/4885GAA 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.