Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094552 | 0.85 | ACACB (0.45) | ALDH1A1SMN1; SMN2CYP3A4THRBHSP90AA1 | |
| SCHEMBL31572047 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP3A4THRBL3MBTL1 | |
| SCHEMBL2534270 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2CYP3A4THRBL3MBTL1 | |
| SCHEMBL5909057 | 0.80 | CA12 (0.58) | ALDH1A1L3MBTL1ACACBRAB9ACA12 | |
| SCHEMBL49805 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2CYP3A4THRBL3MBTL1 | |
| SCHEMBL13753745 | 0.77 | HDAC3 (0.55) | ALDH1A1SMN1; SMN2CYP3A4THRBL3MBTL1 | |
| SCHEMBL10261106 | 0.77 | CA12 (0.49) | ALDH1A1SMN1; SMN2CYP3A4THRBACACB | |
| SCHEMBL20086467 | 0.77 | NPSR1 (0.58) | ALDH1A1SMN1; SMN2CYP3A4L3MBTL1HSD17B10 | |
| SCHEMBL8158111 | 0.76 | NR1H4 (0.54) | ALDH1A1SMN1; SMN2TP53TSHRCA12 | |
| SCHEMBL9525538 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP3A4THRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | ALDH1A1 2561/4885SMN1; SMN2 925/4885CYP3A4 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.