Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 19/20 | 0.82 |
| ▸ | YAP1 | P46937 | 1/20 | 0.61 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.61 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528884 | 0.91 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL15529210 | 0.87 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL18893146 | 0.87 | RXFP1 (0.81) | RXFP1 | |
| SCHEMBL28681534 | 0.82 | RXFP1 (0.83) | RXFP1 | |
| SCHEMBL9268782 | 0.82 | RXFP1 (0.78) | RXFP1YAP1TEAD4TEAD2 | |
| SCHEMBL15529379 | 0.81 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL15528722 | 0.81 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL8416271 | 0.81 | RXFP1 (0.81) | RXFP1 | |
| SCHEMBL15530093 | 0.81 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL10516305 | 0.80 | RXFP1 (0.80) | RXFP1YAP1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | RXFP1 1/4885YAP1 2604/4885TEAD4 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.