Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 16/20 | 0.78 |
| ▸ | YAP1 | P46937 | 1/20 | 0.70 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.70 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528884 | 0.88 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL10516305 | 0.88 | RXFP1 (0.80) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL1774875 | 0.86 | RXFP1 (0.70) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL9270625 | 0.86 | RXFP1 (0.73) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL9522037 | 0.86 | YAP1 (0.74) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL6433823 | 0.86 | GRIK1 (0.75) | RXFP1ALDH1A1MAPTRAB9A | |
| SCHEMBL13754010 | 0.86 | RXFP1 (0.73) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL28473857 | 0.85 | RXFP1 (0.79) | RXFP1 | |
| SCHEMBL30112566 | 0.85 | RXFP1 (0.79) | RXFP1 | |
| Flufenamic Acid SCHEMBL29356958 | 0.85 | RXFP1 (0.75) | RXFP1YAP1TEAD4TEAD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462952-A | Have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |