Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.52 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.52 |
| ▸ | NNMT | P40261 | 2/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.52 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | RNMT | O43148 | 1/20 | 0.52 |
| ▸ | INMT | O95050 | 1/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978098 | 0.85 | DOT1L (0.72) | EHMT2NSD2PCMT1DOT1LSETD7 | |
| SCHEMBL19959561 | 0.84 | POLB (0.63) | ENPP1P2RY1POLBEHMT2NSD2 | |
| SCHEMBL3691593 | 0.84 | POLB (0.64) | ENPP1P2RY1POLBDOT1LHIF1A | |
| Deoxyadenosine SCHEMBL5982298 | 0.82 | HIF1A (0.71) | ENPP1P2RY1POLBDOT1LHIF1A | |
| Deoxyadenosine SCHEMBL19506291 | 0.82 | HIF1A (0.71) | ENPP1P2RY1POLBDOT1LHIF1A | |
| Deoxyadenosine SCHEMBL23982174 | 0.82 | HIF1A (0.71) | ENPP1P2RY1POLBDOT1LHIF1A | |
| SCHEMBL6914336 | 0.82 | POLB (0.63) | ENPP1P2RY1POLBDOT1LHIF1A | |
| Deoxyadenosine SCHEMBL12222447 | 0.82 | HIF1A (0.71) | ENPP1P2RY1POLBDOT1LHIF1A | |
| Deoxyadenosine SCHEMBL21637036 | 0.82 | HIF1A (0.71) | ENPP1P2RY1POLBDOT1LHIF1A | |
| SCHEMBL23547685 | 0.82 | POLB (0.63) | ENPP1P2RY1POLBDOT1LHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242087-B2 | Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-08-14 | — | — | US | disclosed |
| US-20110112046-A9 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-05-12 | — | — | US | disclosed |
| US-20100093656-A1 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112046-A9 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | MTAP, POLRMT, PNP | ENPP1 17/4885P2RY1 575/4885POLB 12/4885 |
| US-20100093656-A1 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | MTAP, POLRMT, PNP | ENPP1 17/4885P2RY1 575/4885POLB 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.