SCHEMBL1889486

SCHEMBL1889486

N#CC(=Cc1cccs1)c1cccs1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.59
RAB9A P51151 5/20 0.59
KMT2A Q03164 6/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 4/20 0.52
LMNA P02545 3/20 0.52
MEN1 O00255 3/20 0.52
POLB P06746 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 1/20 0.44
PKM P14618 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16532914 0.88 NPC1 (0.47) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL11661184 0.88 NPC1 (0.57) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL18010216 0.84 EGFR (0.48) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL16532964 0.83 RAB9A (0.43) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL16532907 0.83 NPC1 (0.43) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL16532878 0.83 NPC1 (0.43) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL16532909 0.82 DPP4 (0.44) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL16532957 0.81 MAPT (0.48) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL4909715 0.81 KMT2A (0.63) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL5425364 0.81 MAPT (0.55) NPC1RAB9AKMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939900-B2 Polymerizable anions and/or cations can be used as the ionically conductive species for the formation of heterojunctions in electroconductive polymer thin films, having high current rectification ratios, electroluminescence with high quantum efficiency and low operating voltage, used as solar cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-05-10 US disclosed
US-20080224089-A1 MATERIALS FOR THE FORMATION OF POLYMER JUNCTION DIODES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-18 US disclosed
WO-2007030679-A2 MATERIALS FOR THE FORMATION OF POLYMER JUNCTION DIODES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-03-15 WO disclosed