Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17352230 | 0.87 | FFAR1 (0.48) | FFAR1F11F2PRSS1PRSS2 | |
| SCHEMBL15514629 | 0.87 | FFAR1 (0.48) | FFAR1F11F2PRSS1PRSS2 | |
| SCHEMBL1330994 | 0.84 | FFAR1 (0.48) | FFAR1SMN1; SMN2DGAT1CA1CA2 | |
| SCHEMBL3663499 | 0.84 | FFAR1 (0.45) | FFAR1SMN1; SMN2DGAT1CA1CA2 | |
| SCHEMBL25251426 | 0.82 | FFAR1 (0.43) | FFAR1SMN1; SMN2DGAT1USP30RXFP1 | |
| SCHEMBL1712762 | 0.82 | FFAR1 (0.46) | FFAR1SMN1; SMN2DGAT1USP30 | |
| SCHEMBL17005480 | 0.81 | FFAR1 (0.52) | FFAR1F11DGAT1 | |
| SCHEMBL17801161 | 0.81 | FFAR1 (0.48) | FFAR1F11F2PRSS1PRSS2 | |
| SCHEMBL875957 | 0.81 | FFAR1 (0.51) | FFAR1CA1CA2CA9CA12 | |
| SCHEMBL30062308 | 0.80 | FFAR1 (0.41) | FFAR1F11F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380469-A1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2018-10-03 | — | — | EP | disclosed |
| WO-2017091661-A1 | BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF | STROVEL JEFFREY WILLIAM (US) | 2017-06-01 | — | — | WO | disclosed |