Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17352230 | 0.85 | FFAR1 (0.48) | FFAR1RXFP1SMN1; SMN2DGAT1KDR | |
| SCHEMBL15514629 | 0.85 | FFAR1 (0.48) | FFAR1RXFP1SMN1; SMN2CA1CA2 | |
| SCHEMBL3663499 | 0.84 | FFAR1 (0.45) | FFAR1RXFP1SMN1; SMN2CA1CA2 | |
| SCHEMBL18895313 | 0.84 | FFAR1 (0.47) | FFAR1RXFP1SMN1; SMN2CA1CA2 | |
| SCHEMBL25251426 | 0.80 | FFAR1 (0.43) | FFAR1RXFP1SMN1; SMN2DGAT1USP30 | |
| SCHEMBL1712762 | 0.80 | FFAR1 (0.46) | FFAR1SMN1; SMN2DGAT1GSK3BGSK3A | |
| SCHEMBL17005480 | 0.79 | FFAR1 (0.52) | FFAR1DGAT1AAK1 | |
| SCHEMBL17801161 | 0.79 | FFAR1 (0.48) | FFAR1DGAT1AAK1USP30 | |
| SCHEMBL875957 | 0.78 | FFAR1 (0.51) | FFAR1CA1CA2CA9CA12 | |
| SCHEMBL30291377 | 0.77 | FFAR1 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569301-A1 | INDAZOLE INHIBITORS OF KINASE | Abbvie Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| US-8293738-B2 | Indazole inhibitors of kinase | ABBOTT LABORATORIES (US) | 2012-10-23 | — | — | US | disclosed |
| US-20110281868-A1 | INDAZOLE INHIBITORS OF KINASE | ABBOTT LABORATORIES (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2011143430-A1 | INDAZOLE INHIBITORS OF KINASE | ABBOTT LABORATORIES (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281868-A1 | INDAZOLE INHIBITORS OF KINASE | AURKA, AURKC, AURKB | FFAR1 4318/4885RXFP1 3136/4885SMN1; SMN2 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.