Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199877 | 0.87 | POLB (0.53) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17725298 | 0.80 | ACACB (0.43) | HPGD | |
| SCHEMBL30865420 | 0.76 | HPGD (0.79) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30865440 | 0.76 | HPGD (0.79) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30865492 | 0.76 | HPGD (0.79) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30865488 | 0.76 | HPGD (0.79) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30865472 | 0.76 | HPGD (0.79) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8551555 | 0.75 | CYP1A2 (0.47) | HPGDKDM4EALDH1A1SMN1; SMN2MLYCD | |
| SCHEMBL9784444 | 0.74 | SMN1; SMN2 (0.84) | NAAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15999997 | 0.74 | SMN1; SMN2 (0.84) | NAAAHPGDALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663466-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |