Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18896237 | 0.87 | NAAA (0.54) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL17725298 | 0.86 | ACACB (0.43) | POLBACACBHRH3HPGDNPC1 | |
| SCHEMBL8551555 | 0.81 | CYP1A2 (0.47) | POLBACACBALDH1A1KDM4EHRH3 | |
| SCHEMBL23799182 | 0.80 | HRH3 (0.39) | ACACBALDH1A1HRH3LMNASMN1; SMN2 | |
| SCHEMBL7876851 | 0.79 | ACACB (0.40) | ACACBALDH1A1HRH3HPGDNPC1 | |
| SCHEMBL15625519 | 0.76 | MCL1 (0.45) | POLBACACBHRH3NAMPTDGAT2 | |
| SCHEMBL16027956 | 0.76 | — | — | |
| SCHEMBL11777365 | 0.75 | SMN1; SMN2 (0.50) | POLBALDH1A1TP53HPGDNPC1 | |
| SCHEMBL23052114 | 0.75 | ACACB (0.49) | ACACBALDH1A1SMN1; SMN2F2R | |
| SCHEMBL24567585 | 0.74 | ACACB (0.54) | POLBACACBALDH1A1HRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866293-A1 | COMPOUNDS COMPRISING AN OXAZOLE OR THIAZOLE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB Pharma, S.A. (BE) | 2007-12-19 | — | — | EP | claimed |
| WO-2006103045-A1 | COMPOUNDS COMPRISING AN OXAZOLE OR THIAZOLE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA S.A. (BE) | 2006-10-05 | — | — | WO | claimed |
| US-20210277061-A1 | YEATS INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277061-A1 | YEATS INHIBITORS AND METHODS OF USE THEREOF | YEATS2, YEATS4, MLLT1 | POLB 1892/4885ACACB 2558/4885ALDH1A1 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.