Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18896295 | 0.91 | BACE1 (0.55) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL18896440 | 0.87 | ERAP2 (0.60) | ANPEPKMT2AMME | |
| SCHEMBL12251345 | 0.84 | KMT2A (0.63) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL4746610 | 0.84 | ANPEP (0.57) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL7432155 | 0.84 | ANPEP (0.57) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL8155147 | 0.84 | ANPEP (0.57) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL21233754 | 0.83 | KMT2A (0.61) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL21233885 | 0.83 | KMT2A (0.61) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL1516159 | 0.83 | MME (0.65) | ANPEPKMT2AMMEMEN1ALDH1A1 | |
| SCHEMBL10031574 | 0.83 | MME (0.65) | ANPEPKMT2AMMEMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662335-B2 | Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-05-30 | — | — | US | disclosed |