Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504030 | 0.78 | — | — | |
| Acrylic Acid SCHEMBL8591892 | 0.73 | ALOX15 (0.62) | ALOX15HSD17B10LDHASRRTSHR | |
| SCHEMBL18896650 | 0.73 | ALOX15 (0.45) | ALOX15HSD17B10LDHASRRTSHR | |
| SCHEMBL28952869 | 0.72 | — | — | |
| SCHEMBL28053344 | 0.71 | ALOX15 (0.48) | ALOX15HSD17B10LDHASRRTSHR | |
| SCHEMBL5450080 | 0.71 | ALOX15 (0.43) | ALOX15HSD17B10LDHASRRTSHR | |
| SCHEMBL14145041 | 0.69 | — | — | |
| Butadiene SCHEMBL28129794 | 0.69 | ALOX15 (0.44) | ALOX15HSD17B10LDHASRRTSHR | |
| SCHEMBL23965480 | 0.68 | — | — | |
| SCHEMBL8814029 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663529-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |