Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59537 | 1.00 | ACE (0.41) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL22966485 | 1.00 | ACE (0.41) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL14211021 | 1.00 | ACE (0.41) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL2032006 | 0.94 | ACE (0.46) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL584218 | 0.85 | ACE (0.44) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL58639 | 0.85 | ACE (0.44) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL584217 | 0.85 | ACE (0.44) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL22966599 | 0.82 | ACE (0.40) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL28299734 | 0.81 | ACE (0.41) | ACERENKDM4ELMNAHSD17B10 | |
| SCHEMBL12202698 | 0.79 | L3MBTL1 (0.48) | ACERENKDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |