Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568588 | 1.00 | ADRB2 (0.57) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568527 | 0.99 | ADRB2 (0.58) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568526 | 0.99 | ADRB2 (0.58) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568548 | 0.93 | ADRB2 (0.56) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568545 | 0.93 | ADRB2 (0.56) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568550 | 0.93 | ADRB2 (0.59) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568552 | 0.93 | ADRB2 (0.59) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL21568522 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1CHRM3 | |
| SCHEMBL21568523 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1CHRM3 | |
| SCHEMBL21568672 | 0.93 | ADRB2 (0.56) | ADRB2ADRB1CHRM3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303333-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2019-11-20 | — | — | EP | claimed |
| US-9662323-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-30 | — | — | US | disclosed |