Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.84 |
| ▸ | CHRM3 | P20309 | 19/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339304 | 1.00 | ADRB2 (0.84) | ADRB2CHRM3 | |
| SCHEMBL18259848 | 1.00 | ADRB2 (0.84) | ADRB2CHRM3 | |
| SCHEMBL18259847 | 1.00 | ADRB2 (0.84) | ADRB2CHRM3 | |
| SCHEMBL18260002 | 0.94 | ADRB2 (0.90) | ADRB2CHRM3 | |
| SCHEMBL18260000 | 0.94 | ADRB2 (0.90) | ADRB2CHRM3 | |
| SCHEMBL28341187 | 0.94 | ADRB2 (0.90) | ADRB2CHRM3 | |
| SCHEMBL18260099 | 0.92 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL18260098 | 0.92 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL28341093 | 0.92 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL18259849 | 0.92 | ADRB2 (0.83) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662323-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-30 | — | — | US | disclosed |