Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897354 | 0.94 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL18897452 | 0.93 | ADRB2 (0.51) | ADRB2CHRM3ADRB1 | |
| SCHEMBL18897336 | 0.88 | ADRB2 (0.53) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568605 | 0.86 | ADRB2 (0.62) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568606 | 0.86 | ADRB2 (0.62) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568653 | 0.86 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568655 | 0.86 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568638 | 0.86 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL21568635 | 0.86 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL18259849 | 0.83 | ADRB2 (0.83) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662323-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-30 | — | — | US | disclosed |