Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | OGT | O15294 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841289 | 0.91 | PGR (0.43) | PGRHTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL17857556 | 0.85 | PGR (0.42) | PGRHTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL17861559 | 0.82 | PGR (0.40) | PGRROCK2 | |
| SCHEMBL16322050 | 0.80 | HTT (0.53) | PGRHTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16322048 | 0.80 | HTT (0.53) | PGRHTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16321359 | 0.77 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16321357 | 0.77 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16364694 | 0.74 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16324040 | 0.73 | SMN1; SMN2 (0.69) | HTTSMN1; SMN2CYP3A4CYP2B6 | |
| SCHEMBL16324039 | 0.73 | SMN1; SMN2 (0.69) | HTTSMN1; SMN2CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663516-B2 | Bicyclic-pyrimidinedione compounds | MyoKardia, Inc. (US) | 2017-05-30 | — | — | US | disclosed |