Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22113080 | 0.86 | CNR2 (0.50) | CNR2CYP2A6PARP10PARP15TNKS2 | |
| SCHEMBL17807765 | 0.83 | CNR2 (0.41) | CNR2PARP10PARP15TNKS2PARP2 | |
| SCHEMBL14086888 | 0.81 | TMEM97 (0.46) | CNR2RAB9ATDP1 | |
| SCHEMBL28091445 | 0.81 | SIGMAR1 (0.41) | CNR2ALDH1A1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL5956419 | 0.77 | SLC6A2 (0.52) | CNR2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9886026 | 0.77 | CYP2A6 (0.44) | CYP2A6PARP10PARP15TNKS2PARP2 | |
| SCHEMBL10365163 | 0.71 | CNR2 (0.49) | CNR2SMN1; SMN2ALDH1A1TSHRTP53 | |
| SCHEMBL3032933 | 0.71 | CNR2 (0.49) | CNR2PARP10PARP15TNKS2PARP2 | |
| SCHEMBL11397522 | 0.71 | PARP10 (0.46) | CYP2A6PARP10PARP15TNKS2PARP2 | |
| SCHEMBL14160826 | 0.69 | NR1I2 (0.54) | NR1I2EGFRADRA2AADORA3TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663520-B2 | Bicyclic bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |