Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | CD2 | P06729 | 1/20 | 0.40 |
| ▸ | CD58 | P19256 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.38 |
| ▸ | ITGAV | P06756 | 12/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177352 | 0.92 | CTSL (0.66) | CTSLDRD1PTGS1PDE4ACD2 | |
| SCHEMBL8354015 | 0.91 | CTSL (0.68) | CTSLDRD1PTGS1PDE4ACD2 | |
| SCHEMBL8356922 | 0.90 | CTSL (0.57) | CTSLDRD1PTGS1PDE4ACD2 | |
| SCHEMBL8354165 | 0.88 | CTSL (0.73) | CTSLDRD1PTGS1PDE4ACD2 | |
| SCHEMBL17253268 | 0.86 | CTSL (0.75) | CTSLDRD1PTGS1PDE4AST14 | |
| SCHEMBL8357546 | 0.86 | CTSL (0.75) | CTSLDRD1PTGS1PDE4AST14 | |
| SCHEMBL8354294 | 0.86 | CTSL (0.75) | CTSLDRD1PTGS1PDE4AST14 | |
| SCHEMBL8242524 | 0.86 | CTSL (0.77) | CTSLDRD1PTGS1PDE4AST14 | |
| SCHEMBL8221749 | 0.85 | CTSL (0.66) | CTSLDRD1PTGS1PDE4AST14 | |
| SCHEMBL17486431 | 0.84 | CTSL (0.67) | CTSLDRD1PTGS1PDE4AST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662397-B2 | Lipopeptide compositions and related methods | MERCK SHARP & DOHME CORP. (US) | 2017-05-30 | — | — | US | disclosed |