Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938086 | 0.85 | ABL1 (1.00) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL27914164 | 0.83 | ABL1 (0.68) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL18899830 | 0.82 | ABL1 (0.52) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL18899903 | 0.82 | ABL1 (0.72) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL16805029 | 0.82 | CYP11B1 (0.69) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL18899940 | 0.81 | ABL1 (0.50) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL18899958 | 0.81 | ABL1 (0.59) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL18900177 | 0.81 | LCK (0.57) | ABL1 | |
| SCHEMBL10288471 | 0.78 | ABL1 (0.66) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL24098399 | 0.78 | DYRK1A (0.56) | ABL1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651899-B1 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2017-05-31 | — | — | EP | disclosed |